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Variable
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Baseline, mean (SD)
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Post-intervention
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Between Group Difference Post intervention
|
|---|
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Mean (SD)
|
Mean (SD)
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P *
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Mean (95% CI)
|
P †
|
|---|
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Age (yrs)
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|
Exercise
|
52.8 (10.6); (n = 50)
|
52.8 (10.6); (n = 48)
|
–
|
–
|
–
|
|
Usual Care
|
53.6 (10.1); (n = 50)
|
53.6 (10.1); (n = 45)
| | | |
|
Systolic blood pressure (mmHg)
| | | | | |
|
Exercise
|
132.9 (13.0)
|
120.7 (9.5)
|
< 0.001*
|
−13.7 (− 16.5 to − 8.7)
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< 0.001†
|
|
Usual Care
|
133.7 (9.7)
|
135.9 (9.8)
|
0.22
| | |
|
hsCRP (mg/L)
|
|
Exercise
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3.4 (0.6)
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2.3 (0.3)
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< 0.001*
|
−1.9 (− 5.2 to − 0.6)
|
< 0.001†
|
|
Usual Care
|
3.7 (0.3)
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4.2 (0.4)
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0.54
| | |
|
Total Cholesterol (mg/dL)
|
|
Exercise
|
196.5 (53.4)
|
157.5 (37.1)
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< 0.001*
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−52.9 (−75.0 to −43.0)
|
< 0.001†
|
|
Usual Care
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194.4 (48.9)
|
210.4 (52.2)
|
0.31
| | |
|
HDL-C (mg/dL)
|
|
Exercise
|
43.1 (6.6)
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64.7 (7.8)
|
< 0.001*
|
24.4 (17.9 to 27.9)
|
< 0.001†
|
|
Usual Care
|
41.0 (4.3)
|
39.9 (4.0)
|
0.45
| | |
|
Hemoglobin A1C (%)
|
|
Exercise
|
7.5 (0.9)
|
2.9 (0.2)
|
< 0.001*
|
−4.6 (−11.2 to −1.6)
|
< 0.001†
|
|
Usual Care
|
7.5 (0.8)
|
7.9 (0.8)
|
0.28
| | |
|
Parent with MI before age 60 years, n (%)
|
|
Exercise
|
40 (80)
|
40 (80)
|
–
|
–
|
–
|
|
Usual Care
|
42 (84)
|
42 (84)
| | | |
|
10-year Risk RRS (%)
|
|
Exercise
|
7.9 (0.9)
|
1.0 (0.5)
|
< 0.001*
|
−10.6 (−16.3 to −7.4)
|
< 0.001†
|
|
Usual Care
|
9.0 (0.8)
|
11.6 (1.2)
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0.002*
| | |
- *P value for repeated-measures ANOVA comparing changes in the exercise group from baseline to post-intervention, and in the usual care group from baseline to post-intervention
- † P value for mixed model analysis comparing changes between the exercise and usual care group from baseline to post-intervention
- Age and parent history of MI before 60 years calculated as unchanged during the 16-week intervention period